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Patients who are more anxious may need a medication that is stronger than nitrous oxide. With sedation, the patient may be sleepy but can be aroused and will respond to simple commands. Minor side effects such as nausea or vomiting can occur with some medications. Before a visit in which a patient is to receive sedation, he/she will receive instructions about eating and drinking, what to expect and what to watch for after treatment. You will need assistance to get home after sedation.